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Pebp4 and heart

WebPEBP4 appears to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. ... Anti-PEBP4 antibody (ab99468) at 1 µg/ml + Human Heart lysates at 35 µg Predicted band size: 26 kDa. WebJul 1, 2016 · In mammalian cells, four members of PEBP, ranging from 21–25 kids, have been documented; PEBP1 is ubiquitously expressed at high levels in the brain, adrenal gland and thyroid [2], [3], PEBP2 is mostly restricted to the testis [4], PEBP3 has not yet been characterized, and PEBP4 is predominantly expressed in the skeletal muscle, heart and ...

PEBP4 Gene - GeneCards PEBP4 Protein PEBP4 Antibody

WebJul 1, 2016 · PEBP4 was first identified as a regulator of the MAPK pathway [5], [20]. Wang et al [5] have shown that PEBP4 interacts with Raf-1 and MEK1 and attenuates activation of … WebOct 26, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4), a member of the PEBP family, has been reported to play a pivotal role in tumor progression. However, its role in epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells remains unclear. Here, we investigated the effects and underlying mechanism of PEBP4 in … lexus in smyrna ga https://rixtravel.com

Phosphatidylethanolamine-binding protein 4 promotes the …

Webpebp4. single cell type lung. adipose tissue bone marrow brain breast bronchus colon endometrium esophagus eye heart muscle. kidney liver lung lymph node ovary pancreas pbmc placenta prostate rectum. salivary gland skeletal muscle skin small intestine spleen stomach testis thymus tongue vascular. cell type proteome. WebJan 20, 2024 · Interaction between whitefly PEBP4 and TYLCV CP suppresses phosphorylation of MAPK cascade, activating apoptosis. TYLCV CP liberates PEBP4 … WebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain undefined.... lexus in sharon ma

Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted …

Category:Phosphatidylethanolamine‐binding protein 4 promotes the …

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Pebp4 and heart

PEBP4 gene expression and its significance in invasion and

WebDec 1, 2024 · PEBP4 is a ubiquitous and evolutionary conserved but scarcely studied protein that like the other PEBP family members (PEBP1-4), potentially binds … WebHeart musclei. On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and …

Pebp4 and heart

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WebPharos : Target Details - PEBP4 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data WebOct 26, 2024 · Furthermore, PEBP4 overexpression significantly promoted the transcriptional activity of sonic hedgehog (Shh) signaling in NSCLC cells. Further analysis showed that using cyclopamine to inhibit Shh signaling significantly ameliorated the effect on cell proliferation, invasion, and migration, as well as EMT triggered by PEBP4 overexpression.

WebMar 21, 2024 · PEBP4 (Phosphatidylethanolamine Binding Protein 4) is a Protein Coding gene. An important paralog of this gene is PEBP1. UniProtKB/Swiss-Prot Summary for …

WebFeb 11, 2024 · PEBP4 directly interacted with the coat protein (CP) of TYLCV Since CP has been shown to be required for successful infection 34, it was used as the bait in yeast two … WebFeb 1, 2007 · PEBP4 (phosphatidylethanolamine binding protein 4) 2007-02-01 Identity HGNC PEBP4 LOCATION 8p21.3 LOCUSID 157310 ALIAS CORK-1, CORK1, GWTM1933, …

WebZi-Kang Luo, 1, * Qiong-Feng Chen, 2, * Xiaoqin Qu, 2 Xiao-Yan Zhou 2, 3 1 Department of Clinical Medical, The Second Clinical Medical College, Nanchang University, Nanchang 330006, People’s Republic of China; 2 Department of Pathophysiology, Medical College of Nanchang University, Nanchang, Jiangxi 330006, People’s Republic of China; 3 Jiangxi …

WebOct 17, 2015 · The PI3K/Akt/mTOR signaling axis may be a key molecular pathway via which PEBP4 promotes the proliferation and invasion of non-small cell lung cancer (NSCLC) … mcculloch blower partsWebThe phosphatidylethanolamine (PE)-b inding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and … mcculloch bhe 900 engineWebSummary of RNA expression and protein localization based on data generated within the Human Protein Atlas project. Main locationi. Main subcellular location (s) and reliability score (s) for the encoded protein (s) in human cells. The main location (s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity ... lexus interior leather repair kitWebThe gene view histogram is a graphical view of mutations across PEBP4. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. lexus instruction manualWebMar 22, 2024 · Serum PEBP4 was high in CKD patients compared with healthy individuals. PEBP4 levels were positively correlated with pathological stage in CKD patients. PEBP4 … mcculloch battery strimmerWeb(E): PEBP4 protein expression was tested by western blotting in the heart, liver, lungs, spleen, and kidneys of WT and CKO mice. Data are presented as mean ± SD values (n = 3). … mcculloch blower mb3202WebNov 12, 2011 · PEBP4 is expressed in the mammalian testis, heart, skeletal muscle, thyroid, liver, spinal cord, brain, adrenal gland, and bone marrow [ 14 ], and mainly participates in physiopathological processes such as membrane biosynthesis, neurodevelopment, spermatogenesis, and apoptosis [ 4 ]. lexus interface