Lysocellin
WebLysocellin was first reported in the literature by Ebata, et al, The Journal of Antibiotics 28 (2):118-121, 1975. The physico-chemical properties of lysocellin are described there, including a melting point of about 158°-160° C. of the colorless needles of the sodium salt. WebApr 1, 2006 · Lysocellin up-regulates p21WAF1/Cip1 and down-regulates cyclin D1 at the mRNA level. In addition, cyclin D1 is down-regulated by the proteasome-dependent signal pathway in MG63 cells. In drug combination studies, we found that lysocellin treatment weakened the cytotoxic activity of etoposide in MG63 cells using a colony-formation assay.
Lysocellin
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Websin or lysocellin. Growth of two strains each of Ruminococcus flavefaciens and Butyrivibrio fibrisolvew in broth media was inhibited by 2pg monen- sin/ml (2 ppm), whereas this … WebJan 8, 1996 · Stereoselective total synthesis of lysocellin ( 1 ), a representative polyether antibiotic, was achieved via coustruction of substituted tetrahydrofuran and γ-lactol rings …
WebLysocellin was obtained as a colorless crystalline needles from both the cultural filtrate and the mycelium of the organism. The antibiotic melted at 158 similar to 160 degrees C and had a molecular formula C34H59O10Na-1/2H2O. WebWe describe lysocellin, a divalent polyether antibiotic, and the newly discovered drug ‘alopestatin’, isolated from Streptomyces sp. NA34896. Lysocellin is well known as a carboxylic ionophore that has been shown to improve the performance of beef cattle fed diets based on silage or concentrate (11,12). We newly found that lysocellin induces
WebThe lysocline is the depth in the ocean dependent upon the carbonate compensation depth (CCD), usually around 3.5 km, below which the rate of dissolution of calcite increases … WebA process for promoting growth and feed efficiency in food producing animals is provided by administering to such animals, growth promoting amounts of certain forms of lysocellin, including the free acid and physiologically-acceptable salts thereof.Metal complexes of lysocellin can be prepared by adding the appropriate soluble metal salts to a …
WebSep 15, 1992 · Total synthesis of the polyether antibiotic lysocellin. 2. Stereocontrolled synthesis of the C10-C23 fragment and its aldol condensation with the C1-C9 fragment to complete the total synthesis of lysocellin - ScienceDirect Tetrahedron Letters Volume 33, Issue 38, 15 September 1992, Pages 5541-5544
WebLysocellin at 0 or 22 mg/kg and Ca at .3 or .6% of the diet were fed in a 2 x 2 factorial arrangement of treatments. Two steers averaging 287 kg BW were fed each diet consisting of 80% corn... footprints arena official websiteWebNov 11, 2011 · In an effort to gain further insight into factors that cause increased ruminal propionate when ionophores are fed to ruminants, ruminal bacteria were tested for their … footprints black river fallsWebJan 8, 1996 · Stereoselective total synthesis of lysocellin ( 1 ), a representative polyether antibiotic, was achieved via coustruction of substituted tetrahydrofuran and γ-lactol rings and final aldol condensation. Graphical abstract A stereoselective total synthesis of lysocellin ( 1) was achieved via a coupling of C1–C9 ( 2) and C10–C23 subunits ( 3 ). elft charter houseWebGoogle Patents:Process to produce lysocellin PubMed:Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide. PubMed:Isolation and characterization of four polyether antibiotics, X-14889A, B, C, and D, closely related to lysocellin and the ferensimycins. PubMed:Three novel polyether … footprints around the worldWebNov 11, 2011 · In additional studies, Fibrobacter succinogenec and Lachnospira multiparus were more resistant to lysocellin than to monensin, while B. fibrisolvens, M. elsdenii, Ruminococcus flavefaciens, Ruminobacter amylophilus, Selenomonas ruminantium, Selenomonas lactolytica and Streptococcus bovis had similar sensitivity whereas … footprints beachside recoveryWebMar 1, 1991 · Lysocellin at 0 or 22 mg/kg and Ca at .3 or .6% of the diet were fed in a 2 x 2 factorial arrangement of treatments. Two steers averaging 287 kg BW were fed each diet consisting of 80% corn... footprints beachside recovery centerWebSep 1, 1991 · Stereoselective total synthesis of lysocellin, the representative polyether antibiotic of the lysocellin family. Part 2. Synthesis of C10–C23 subunit via construction … footprints beachside recovery reviews