WebMar 12, 2024 · FLT3 fms related receptor tyrosine kinase 3 Gene ID: 2322, updated on 12-Mar-2024 Gene type: protein coding Also known as: FLK2; STK1; CD135; FLK-2. See all … WebApr 1, 2024 · FLT3 is a gene change, or mutation, in leukemia (blood cancer) cells. It’s the most common genetic change in acute myeloid leukemia (AML), a type of leukemia that …
FLT3 Gene - GeneCards FLT3 Protein FLT3 Antibody
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3 with fms standing for "feline McDonough sarcoma"), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. FLT3 is a cytokine receptor which belongs to … See more FLT3 is composed of five extracellular immunoglobulin-like domains, an extracellular domain, a transmembrane domain, a juxtamembrane domain and a tyrosine-kinase domain consisting of 2 lobes that are … See more CD135 is a class III receptor tyrosine kinase. When this receptor binds to FLT3L a ternary complex is formed in which two FLT3 molecules are bridged by one (homodimeric) FLT3L. The formation of such complex brings the two intracellular domains in close … See more • Kazi JU, Rönnstrand L (2024). "FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications". Physiol Rev. 99 (3): 1433–1466. doi: • Reilly JT (2003). "FLT3 and … See more Cell surface marker Cluster of differentiation (CD) molecules are markers on the cell surface, as recognized by … See more • Cluster of differentiation • cytokine receptor • receptor tyrosine kinase • tyrosine kinase See more • CD135+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human FLT3 genome location and See more WebOct 9, 2024 · Chromosome 19 - NC_000019.10. Genomic regions, transcripts, and products. ... Location: 29 → 159 Flt3_lig; flt3 ligand; NM_001204503.2 → … bollywood sports movies
FLT3-TKD mutation in childhood acute myeloid leukemia
WebYou can see various sequences for this gene: cDNA (ENST00000241453.11) Protein (FLT3) Transcript and protein aligned (ENST00000241453.11+FLT3) Gene fusions. No fusions involving … WebFLT3-ITD is associated with leukocytosis and a poor prognosis, especially in patients with normal karyotype. Recently, there have been three reports on point mutations at codon 835 of the FLT3 gene (D835 mutations) in adult AML. These mutations are located in the activation loop of the second tyrosine kinase domain (TKD) of FLT3 (FLT3-TKD). WebMar 12, 2024 · Location: 13q12.2 Sequence: Chromosome: 13; NC_000013.11 (28003274..28100576, complement) Total number of exons: 27 Genomic Sequence Go to nucleotide Graphics FASTA GenBank An internal error has occurred that prevents Sequence Viewer from displaying. Technical details (seqconfig error): Application cannot … gm 454 ls6 cam specs