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Cyp17a1蛋白

Web抗cyp17a1抗体(d-12)在各种科学出版物中有12篇引文。 针对哺乳动物靶标蛋白的一抗,如抗cyp17a1 抗体 (d-12),推荐用于检测一系列哺乳动物物种,主要有小鼠,大鼠和人物种。 许多哺乳动物抗体也非常适合兽医研究,与羊、猪、羊、猫、犬、牛和马的蛋白靶点反应。 细胞色素 P450 17A1(英語:Cytochrome P450 17A1)也被称为甾体17α-单加氧酶(steroid 17α-monooxygenase),17α-羟基化酶(17α-hydroxylase),17,20-碳链裂解酶(17,20-lyase 或 17,20-desmolase)是一种羟基化酶,由位于人类10号染色体的 CYP17A1 基因编码 。这一基因在许多组织与细胞中都有表达,特别是肾上腺皮质的网状带(英语:zona reticularis)和 …

CYP17A1 - 维基百科,自由的百科全书

http://yuxiqbs.cqvip.com/Qikan/Search/Index?key=A%3d%e7%a8%8b%e6%b1%89%e5%85%b4 Web发明领域. 本发明涉及制备苯并咪唑化合物,其用作p300和/或CBP活性调节剂和因此能够用作药物物质。 发明背景 hanseatic bank genialcard konditionen https://rixtravel.com

CYP17A1 - 維基百科,自由的百科全書

CYP17A1 is a 57.4 kDa protein that belongs to the cytochrome P450 family. The protein encoded by its cDNA is composed of 508 amino acid residues. As an enzyme, CYP17A1 possesses an active site that associates with a heme prosthetic group to catalyze biosynthetic reactions. See more Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the … See more Gene The CYP17A1 gene resides on chromosome 10 at the band 10q24.3 and contains 8 exons. The cDNA of this gene spans a length of 1527 bp. This gene encodes a member of the cytochrome P450 superfamily … See more CYP17A1 is a member of the cytochrome P450 superfamily of enzymes localized in the endoplasmic reticulum. Proteins in this family are monooxygenases that catalyze synthesis of cholesterol, steroids and other lipids and are involved in drug metabolism. CYP17A1 has both … See more • Pregnenolone • 17α-Hydroxypregnenolone • Progesterone • 17α-Hydroxyprogesterone See more Expression of CYP17A1 has been found in all of the traditional steroidogenic tissues except the placenta, including the zona reticularis and zona fasciculata of the adrenal cortex, the Leydig cells of the testes, the thecal cells of the ovaries, and, more recently, in See more Mutations in this gene are associated with rare forms of congenital adrenal hyperplasia, specifically 17α-hydroxylase deficiency/17,20-lyase deficiency and isolated 17,20-lyase deficiency See more CYP17A1 inhibitors Currently, the FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal … See more WebApr 9, 2024 · 本研究主要探讨新疆阿魏中的化学物质、抗癌的作用机制及可能作用的靶点,通过网络药理学研究帮助筛选新疆阿魏的药效物质基础,对进一步研究其抗肿瘤作用单体成分及作用靶点提供理论基础。. 1方法. 1.1新疆阿魏有效成分及靶点的筛选. 利用草药-中医证候 ... Web把经过封闭的蛋白膜与稀释好的一抗4℃缓慢摇动过夜或室温缓慢摇动2小时,确保稀释的抗体至少能在摇动的瞬间覆盖蛋白膜。 ... CYP17A1 Rabbit Polyclonal Antibody. AF8067. 50μl. StAR Rabbit Polyclonal Antibody. AF6228. 50μl. ARF6 Rabbit Polyclonal Antibody. AF6234. 50μl. ASC/TMS1 Rabbit Polyclonal ... hanselmann house plan section elevation

CYP17A1 (E6Y3S) Rabbit mAb Cell Signaling …

Category:制备P300和/或CBP调节剂的方法【掌桥专利】

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Cyp17a1蛋白

CYP17A1 - 维基百科,自由的百科全书

WebFeb 22, 2024 · 结构 [] 基因 []. CYP17A1 基因位于10号染色体的10q24.3带上包含有8个外显子 ,其cDNA全长为1527bp。. 蛋白 []. CYP17A1蛋白大小为57.4kDa ,包含有508个氨基酸残基,属于CYP450超家族 ,带有一个血红素相关活性位点以催化相关生物反应 。. CYP17A1可被两种甾类抑制剂 阿比特龙 ( 英语 : abiraterone ) 和galeterone特异 ... WebCYP17A1 CRISPR 质粒 (h) 可提供目标特异的基因敲除和激活的CRISPR质粒。. 请参考下面标签中详细的产品信息. 除慢病毒激活颗粒外,其他产品均为转染即用型纯化DNA质粒。. 慢病毒激活颗粒预包被成慢病毒颗粒的形式,适用于难被转染的细胞.

Cyp17a1蛋白

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WebFeb 22, 2024 · CYP17A1 ;, CPT7, CYP17, P450C17, S17AH, cytochrome P450 family 17 subfamily A member 1 外部ID OMIM : 609300 MGI : 88586 HomoloGene : 73875 GeneCards : CYP17A1 Web肾上腺皮质腺瘤CYP17A1及3BHSD2蛋白的免疫组化研究. 目的:应用免疫组织化学染色方法观察17α羟化酶 (CYP17A1),3β羟基类固醇脱氢酶2 (3BHSD2)在人正常肾上腺及其肿瘤组织中的分布特点,探讨CYP17A1,3BHSD2免疫组化检测对病理诊断肾上腺醛固酮分泌腺瘤 (APA),皮质醇分泌腺瘤 ...

http://www.jinpanmed.cn/archives/date/2024/04/11 Web说明书. CYP17A1 抗体 D-12 是小鼠单克隆 IgG 2a κ, CYP17A1抗体, 在 12篇文献中引用 ,规格为 200 µg/ml. 免疫原氨基酸序列461-508位于human物种的CYP17A1的C …

WebApr 11, 2024 · amresco 0312-100g bromophenol blue sodium salt 溴酚蓝,钠盐 WebSep 26, 2024 · cyp17a1是雄激素产生过程中最重要的酶,而阿比特龙是针对此酶的抑制剂。 当CYP17A1酶被抑制以后,雄激素的产生将受阻。 恩杂鲁胺则是靶向作用于雄激素受体(AndrogenReceptor,AR)上的LBD结构域,使雄激素不能与AR结合,阻断AR信号通路。

Webcyp17a1蛋白属于细胞色素p450氧化酶超家族的一员,定位于内质网,既有甾体的17α-羟化酶也有17,20-裂合酶活性,在类固醇生成途径中将孕烯醇酮或孕酮的d环上17号c原子上α …

Webcyp17a1蛋白屬於細胞色素p450氧化酶超家族的一員,定位於內質網,既有甾體的17α-羥化酶也有17,20-解離酶活性,在類固醇生成途徑中將孕烯醇酮或孕酮的d環上17號c原子上α位加上一個羥基(-oh)基團,生成17α-羥孕烯醇酮或17α-羥孕酮(17α-羥基化活性);之後再 ... hans shirtsWebFunction. A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis ( PubMed: 9452426, PubMed: 27339894, PubMed: 22266943, PubMed: 25301938 ). Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an … hansen plastics corp elgin ilWebDec 1, 2024 · Cyp17a1 (Cytochrome P450 family 17 subfamily A member 1) is thought to play essential roles in fish steroidogenesis. Therefore, to further understand its roles in steroidogenesis, sex determination, and fertility in fish, we constructed a cyp17a1 gene mutant in Nile tilapia (Oreochromis niloticus). In XX fish, mutation of the cyp17a1 gene … hansford butchers cheddarhttp://kns55.zh.eastview.com/kcms/detail/detailall.aspx?filename=1021623197.nh&dbcode=CMFD&dbname=CMFDTEMP hansen family crest norwayWebThe CYP17A1 gene provides instructions for making a member of the cytochrome P450 enzyme family. Like other cytochrome P450 enzymes, CYP17A1 is involved in the … hansel and gretel witch hunters 2 releaseWebcyp11b2编码一种多功能蛋白酶,兼具11β-羟化酶、18-羟化酶、18氧化酶和醛固酮合成酶活性。 (3)cyp17a1(p450c17)基因:人类cyp17a1基因定位于10q24.3,包含8个外显子和7个内含子,基因全长6.6kb。cyp17a1编码的蛋白酶兼具17α-羟化酶和17,20-裂解酶的活性。 hanska coop explosionWeb进一步实验证实CPSF6是通过APA调节作用于下游靶点基因人宫颈癌癌基因2(HCCR2),使其具有缩短3'UTR的转录本高表达,翻译更多的蛋白,进而调节肝癌的增殖和转移过程。另外,实验中发现let-7a、let-7c、miR-26a三种miRNA结合在CPSF6基因3'UTR上直接抑制基因的 … hansen\u0027s cherry bush