WebSep 25, 2007 · Human colonic epithelial cell renewal, proliferation, and differentiation are stringently controlled by numerous regulatory pathways. To identify genetic programs of human colonic epithelial cell differentiation in vivo as well as candidate marker genes that define colonic epithelial stem/progenitor cells and the stem cell niche, we applied gene … WebJun 6, 2024 · Proper course of folliculogenesis and oogenesis have an enormous impact on female fertility. Both processes take place in the ovary and involve not only the maturing germ cell, but also few types of somatic cells that assist the ovarian processes and mediate the dialog with the oocyte. These cells, granulosa and theca, are heavily involved in …
Cell Proliferation - an overview ScienceDirect Topics
WebCell cycle deregulation and impaired cell cycle checkpoints are two of the most common causes of aberrant cell proliferation. Cell proliferation can be measured by quantifying protein levels of key proliferation markers … The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation, and can be used in immunohistochemistry. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases … recyclinghof tiengen
Single-cell analysis reveals urothelial cell heterogeneity and
WebCytotoxic T lymphocytes (CTLs) often called CD8 + T cells, are a critical component of the adaptive immune system and play an important role in immune defense against intracellular pathogens such as viruses and bacteria and against tumors [].Like helper CD4 + T cells (e.g., Th1, Th2, Th9, Th17, Th22, Tfh, and Treg), they are generated in the thymus and … WebOct 6, 2024 · These genes were not included in the refined list of proliferation markers used for calculating pseudo-proliferation index because they did not consistently correlate with NCI60 growth rates, but they strongly correlate with relative cell proliferation when integrating more cell lines and more data sets. WebAn introduction to the mechanisms of apoptotic cell death and apoptosis assays and markers. Apoptosis is a form of programmed cell death that has important roles in development, aging, and disease. Apoptosis is initiated by a tightly regulated signaling cascade that results in caspase activation. Several features characterize apoptosis ... recyclinghof tiefenbach passau